João Félix is uncertain for the initial leg of Barcelona's Champions League round-of-16 clash against Napoli after sustaining ligament sprains in his ankle during Tuesday's training session.

Sources suggest the 24-year-old forward may face an absence of approximately one month, potentially ruling him out for the Stadio Diego Armando Maradona match on Feb. 21, with the second leg scheduled for March 12 at the Olympic Stadium in Barcelona.

Having joined on loan from Atletico Madrid in August, Félix has been a regular contributor for Barça this season, scoring seven goals in 28 appearances.

Adding to Barcelona's injury concerns, left-back Alejandro Balde will be sidelined for the remainder of the season following surgery for a hamstring injury.

Balde's operation took place in Finland on Tuesday, and the recovery period is expected to be around four months. However, there is still a possibility that he could participate in the European Championships for Spain if selected.

Félix and Balde now join a growing list of absentees for Barcelona coach Xavi Hernández, who announced his departure from the club in the summer.

Gavi is out for the rest of the campaign due to an ACL tear, while Marcos Alonso is set to miss an extended period after back surgery.

Raphinha and Sergi Roberto are also nursing injuries, but Xavi remains optimistic about the potential return of defender Iñigo Martínez and goalkeeper Marc-André ter Stegen in the near future.

"Iñigo won't be ready for Osasuna on Wednesday but he will be available for Alavés at the weekend," Xavi said.

The Barcelona manager also revealed centre-back Andreas Christensen has been playing with discomfort to help the team.

"We will maybe have Marc back for Granada in La Liga [on Feb. 11]."

After the surprising 5-3 home defeat against Villarreal on Saturday, Barcelona is set to host Osasuna at the Olympic Stadium before embarking on a journey to Vitoria for a clash against Alavés.

Subsequently, they will have home encounters against Granada and an away match against Celta Vigo. These fixtures precede their pivotal Champions League knockout tie against Napoli, marking their first such encounter since 2021.